Malformations of cortical development.
نویسنده
چکیده
Malformations of cortical development (MCD) have been increasingly identified. The purpose of this presentation is to review the current knowledge of the MCD. Before we address this issue, we will briefly present a review of cortical development. The second part of this presentation will address the most important MCD. Finally, the last part of this presentation will address the correlation between MCD and epilepsy.
منابع مشابه
Morphological neuroimaging of malformations of cortical development.
Malformations of cortical development are classified on the basis of imaging features and stages of cortical development. They are grouped by causes of the malformation: abnormal glial and neuronal proliferation, abnormal neuronal migration and abnormal cortical organisation. Focal or multifocal and generalised forms are recognised in each of these groups. In the first group, generalised forms ...
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− Malformations of cortical development are classified on the basis of imaging features and stages of cortical development. They are grouped by causes of the malformation: abnormal glial and neuronal proliferation, abnormal neuronal migration and abnormal cortical organisation. Focal or multifocal and generalised forms are recognised in each of these groups. In the first group, generalised form...
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Cortical Malformations and Networks. Malformations of cortical development (MCD) are highly epileptogenic brain lesions and patients usually become resistant to antiepileptic drug treatment. The histopathological spectrum of MCDs is large, ranging from prominent to only minute lesions. The association between MCDs and epileptogenesis has not been clarified so far but recent data promote the ide...
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Malformations of cortical development are rare congenital anomalies of the cerebral cortex, wherein patients present with intractable epilepsy and various degrees of developmental delay. Cases show a spectrum of anomalous cortical formations with diverse anatomic and morphological abnormalities, a variety of genetic causes, and different clinical presentations. Brain magnetic resonance imaging ...
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Glioneuronal malformations (malformations of cortical development [MCD]) include focal cortical dysplasias (FCD) as well as highly differentiated glioneuronal tumors (i.e. gangliogliomas) and constitute frequent findings in patients with pharmacoresistent focal epilepsies. Tailored resection strategies evolved as promising treatment options and allow a systematic neuropathologic and molecular b...
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ورودعنوان ژورنال:
- Arquivos de neuro-psiquiatria
دوره 67 2B شماره
صفحات -
تاریخ انتشار 2009